Downregulation of nuclear expression of the p33(ING1b) inhibitor of growth protein in invasive carcinoma of the breast

Background/Aims: The inhibitor of growth gene 1 (ING1) is a modulator of cell cycle checkpoints, apoptosis, and cellular senescence. The most widely expressed ING1 isoform is p33(ING1b), which can modulate p53, a molecule that is frequently altered in breast cancer. Reduced ING1 mRNA expression has...

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Autores principales: Nouman, G S, Anderson, J J, Crosier, S, Shrimankar, J, Lunec, J, Angus, B
Formato: Artigo
Lenguaje:Inglês
Publicado: Copyright 2003 Journal of Clinical Pathology 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1770004/
https://ncbi.nlm.nih.gov/pubmed/12835295
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