Redirected infection of directly biotinylated recombinant adenovirus vectors through cell surface receptors and antigens

The inability of adenovirus to infect primitive hematopoietic cells presents an obstacle to the use of adenovirus vectors for gene transfer to these cell types. Therefore, expanding the tropism of adenovirus vectors to unique cell surface antigens would be an important development for gene therapy p...

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Bibliographic Details
Main Authors: Smith, Jeffrey S., Keller, Jonathan R., Lohrey, Nancy C., McCauslin, Christine S., Ortiz, Mariaestela, Cowan, Kenneth, Spence, Sally E.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 1999
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC17697/
https://ncbi.nlm.nih.gov/pubmed/10430860
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