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Divergent Evolution Within Protein Superfolds Inferred from Profile-based Phylogenetics

Many dissimilar protein sequences fold into similar structures. A central and persistent challenge facing protein structural analysis is the discrimination between homology and convergence for structurally similar domains that lack significant sequence similarity. Classic examples are the OB-fold an...

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Bibliografiske detaljer
Main Authors: Theobald, Douglas L., Wuttke, Deborah S.
Format: Artigo
Sprog:Inglês
Udgivet: 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1769326/
https://ncbi.nlm.nih.gov/pubmed/16266719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2005.08.071
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