γ-Aminobutyric acid, acting through γ-aminobutyric acid type A receptors, inhibits the biosynthesis of neurosteroids in the frog hypothalamus

Most of the actions of neurosteroids on the central nervous system are mediated through allosteric modulation of the γ-aminobutyric acid type A (GABA(A)) receptor, but a direct effect of GABA on the regulation of neurosteroid biosynthesis has never been investigated. In the present report, we have a...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Do-Rego, J. L., Mensah-Nyagan, G. A., Beaujean, D., Vaudry, D., Sieghart, W., Luu-The, V., Pelletier, G., Vaudry, H.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17677/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11087816/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.240269897
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