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γ-Aminobutyric acid, acting through γ-aminobutyric acid type A receptors, inhibits the biosynthesis of neurosteroids in the frog hypothalamus

Most of the actions of neurosteroids on the central nervous system are mediated through allosteric modulation of the γ-aminobutyric acid type A (GABA(A)) receptor, but a direct effect of GABA on the regulation of neurosteroid biosynthesis has never been investigated. In the present report, we have a...

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Detalhes bibliográficos
Main Authors: Do-Rego, J. L., Mensah-Nyagan, G. A., Beaujean, D., Vaudry, D., Sieghart, W., Luu-The, V., Pelletier, G., Vaudry, H.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC17677/
https://ncbi.nlm.nih.gov/pubmed/11087816
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