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Construction and characterization of mutants of Salmonella typhimurium deficient in DNA repair of O6-methylguanine.

Escherichia coli has two O6-methylguanine DNA methyltransferases that repair alkylation damage in DNA and are encoded by the ada and ogt genes. The ada gene of E. coli also regulates the adaptive response to alkylation damage. The closely related species Salmonella typhimurium possesses methyltransf...

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Bibliographic Details
Published in:J Bacteriol
Main Authors: Yamada, M, Sedgwick, B, Sofuni, T, Nohmi, T
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1995
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176767/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7883708/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.177.6.1511-1519.1995
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