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The end of the cob operon: evidence that the last gene (cobT) catalyzes synthesis of the lower ligand of vitamin B12, dimethylbenzimidazole.

The cob operon of Salmonella typhimurium includes 20 genes devoted to the synthesis of adenosyl-cobalamin (coenzyme B12). Mutants with lesions in the promoter-distal end of the operon synthesize vitamin B12 only if provided with 5,6-dimethylbenzimidazole (DMB), the lower ligand of vitamin B12. In th...

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Bibliografiske detaljer
Udgivet i:J Bacteriol
Principais autores: Chen, P, Ailion, M, Weyand, N, Roth, J
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1995
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176760/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7883701/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.177.6.1461-1469.1995
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