Formyltetrahydrofolate hydrolase, a regulatory enzyme that functions to balance pools of tetrahydrofolate and one-carbon tetrahydrofolate adducts in Escherichia coli.

The enzyme encoded by Escherichia coli purU has been overproduced, purified, and characterized. The enzyme catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to FH4 and formate. Formyl-FH4 hydrolase thus generates the formate that is used by purT-encoded 5'-phosphoribosylglycinamide...

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Bibliografske podrobnosti

izdano v:	J Bacteriol
Principais autores:	Nagy, P L, Marolewski, A, Benkovic, S J, Zalkin, H
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1995
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176736/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7868604/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.177.5.1292-1298.1995
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