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Heterologous expression of an engineered biosynthetic pathway: functional dissection of type II polyketide synthase components in Streptomyces species.

Polyketides are an extensive class of secondary metabolites with diverse molecular structures and biological activities. A plasmid-based multicomponent polyketide synthase expression cassette was constructed using a subset of actinorhodin (act) biosynthetic genes (actI-orf1, actI-orf2, actI-orf3, ac...

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Bibliografische gegevens
Gepubliceerd in:J Bacteriol
Hoofdauteurs: Kim, E S, Cramer, K D, Shreve, A L, Sherman, D H
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 1995
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176724/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7868592/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.177.5.1202-1207.1995
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