Site-directed mutagenesis of histidine residues in Clostridium perfringens alpha-toxin.

Mutagenesis of H-68 or -148 in Clostridium perfringens alpha-toxin resulted in complete loss of hemolytic, phospholipase C, sphingomyelinase, and lethal activities of the toxin. These activities of the variant toxin at H-126 or -136 decreased by approximately 100-fold of the activities of the wild-t...

Descripción completa

Detalles Bibliográficos

Publicado en:	J Bacteriol
Autores principales:	Nagahama, M, Okagawa, Y, Nakayama, T, Nishioka, E, Sakurai, J
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1995
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176721/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7868589/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.177.5.1179-1185.1995
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!