What does tumour necrosis factor excess do to the immune system long term?

Members of the tumour necrosis factor (TNF)/TNF-receptor (TNF-R) superfamily coordinate the immune response at multiple levels. For example, TNF, LTα, LTß and RANKL provide signals required for lymphoid neogenesis, CD27, OX-40, 4-1BB and CD30 deliver costimulatory signals to augment immune responses...

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Bibliographic Details
Main Authors: Clark, J, Vagenas, P, Panesar, M, Cope, A
Format: Artigo
Language:Inglês
Published: 2005
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1766919/
https://ncbi.nlm.nih.gov/pubmed/16239393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2005.042523
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