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PEGylated recombinant human soluble tumour necrosis factor receptor type I (r-Hu-sTNF-RI): novel high affinity TNF receptor designed for chronic inflammatory diseases
The proinflammatory cytokine, tumour necrosis factor α (TNFα) has been shown to play a pivotal part in mediating acute and chronic inflammation. The activities of TNFα are modulated by the proteolytic shedding of the soluble extracellular domains of the two TNF receptors, p55 sTNF-RI and p75 sTNF-RI...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1766570/ https://ncbi.nlm.nih.gov/pubmed/10577978 |
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