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Functional analysis of putative beta-ketoacyl:acyl carrier protein synthase and acyltransferase active site motifs in a type II polyketide synthase of Streptomyces glaucescens.

The significance of potential active site motifs for acyltransferase and beta-ketoacyl:acyl carrier protein synthase regions within the TcmK protein was investigated by determining the effects of mutations in the proposed active sites on the production of tetracenomycins F2 and C. In a Streptomyces...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Meurer, G, Hutchinson, C R
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176615/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7814341/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.177.2.477-481.1995
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