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Monoalkyl sulfates as alkylating agents in water, alkylsulfatase rate enhancements, and the “energy-rich” nature of sulfate half-esters

Alkyl sulfate monoesters are involved in cell signaling and structure. Alkyl sulfates are also present in many commercial detergents. Here, we show that monomethyl sulfate acts as an efficient alkylating agent in water, reacting spontaneously with oxygen nucleophiles >100-fold more rapidly than d...

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Detalhes bibliográficos
Main Authors: Wolfenden, Richard, Yuan, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1765482/
https://ncbi.nlm.nih.gov/pubmed/17182738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609644104
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