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Natural selection for rash-forming genotypes of the varicella-zoster vaccine virus detected within immunized human hosts

The Oka vaccine strain is a live attenuated virus that is routinely administered to children in the United States and Europe to prevent chickenpox. It is effective and safe but occasionally produces a rash. The vaccine virus has accumulated mutations during its attenuation, but the rashes are not ex...

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Detalhes bibliográficos
Main Authors: Quinlivan, Mark L., Gershon, Anne A., Al Bassam, Mahmoud M., Steinberg, Sharon P., LaRussa, Philip, Nichols, Richard A., Breuer, Judith
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1765436/
https://ncbi.nlm.nih.gov/pubmed/17182747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605688104
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