Beta-lactamase stability of cefpirome (HR 810), a new cephalosporin with a broad antimicrobial spectrum.

Cefpirome was highly stable to hydrolysis by various beta-lactamases, although it was hydrolyzed to some extent by R plasmid-mediated penicillinase of Richmond-Sykes type Va/b and by chromosomal cephalosporinases from Bacteroides species. The compound had a very low affinity for cephalosporinases fr...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Autores principales:	Kobayashi, S, Arai, S, Hayashi, S, Fujimoto, K
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1986
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176519/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3492175/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.30.5.713
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