A randomized multi-center phase II trial of the angiogenesis inhibitor Cilengitide (EMD 121974) and gemcitabine compared with gemcitabine alone in advanced unresectable pancreatic cancer

BACKGROUND: Anti-angiogenic treatment is believed to have at least cystostatic effects in highly vascularized tumours like pancreatic cancer. In this study, the treatment effects of the angiogenesis inhibitor Cilengitide and gemcitabine were compared with gemcitabine alone in patients with advanced...

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Main Authors: Friess, Helmut, Langrehr, Jan M, Oettle, Helmut, Raedle, Jochen, Niedergethmann, Marco, Dittrich, Christian, Hossfeld, Dieter K, Stöger, Herbert, Neyns, Bart, Herzog, Peter, Piedbois, Pascal, Dobrowolski, Frank, Scheithauer, Werner, Hawkins, Robert, Katz, Frieder, Balcke, Peter, Vermorken, Jan, van Belle, Simon, Davidson, Neville, Esteve, Albert Abad, Castellano, Daniel, Kleeff, Jörg, Tempia-Caliera, Adrien A, Kovar, Andreas, Nippgen, Johannes
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2006
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1764757/
https://ncbi.nlm.nih.gov/pubmed/17156477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-6-285
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