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Efficacy of ciprofloxacin in experimental aortic valve endocarditis caused by a multiply beta-lactam-resistant variant of Pseudomonas aeruginosa stably derepressed for beta-lactamase production.

The emergence of multi-beta-lactam resistance is a limiting factor in treating invasive Pseudomonas infections with newer cephalosporins. The in vivo efficacy of ciprofloxacin, a new carboxy-quinolone, was evaluated in experimental aortic valve endocarditis caused by a strain of Pseudomonas aerugino...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Bayer, A S, Lindsay, P, Yih, J, Hirano, L, Lee, D, Blomquist, I K
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1986
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176474/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3539007/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.30.4.528
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