SYSTEMIC POLYETHELENE GLYCOL-MODIFIED (PEGYLATED) -SUPEROXIDE DISMUTASE AND -CATALASE MIXTURE ATTENUATES RADIATION PULMONARY FIBROSIS IN THE C57BL/6 MOUSE

PURPOSE: Since oxidative injury is implicated in radiation-induced tissue damage to the lung, we studied systemically administered polyethylene glycol (PEG-ylated) antioxidant enzymes (AOEs) as pulmonary radioprotectors in mice. METHODS AND MATERIALS: C57Bl Mice received 13.5 Gy single-dose irradiat...

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Hauptverfasser: Machtay, M., Scherpereel, A., Santiago, J., Lee, J., McDonough, J., Kinniry, P, Arguiri, E, Shuvaev, V.V., Sun, J., Cengel, K., Solomides, C.C., Christofidou-Solomidou, M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1764603/
https://ncbi.nlm.nih.gov/pubmed/17069914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.radonc.2006.09.01
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