Factors influencing the in vitro activity of two new aryl-fluoroquinolone antimicrobial agents, difloxacin (A-56619) and A-56620.

The in vitro activity of difloxacin (A-56619) and A-56620, two new aryl-difluoroquinolones, was decreased by magnesium at 9 mM and in assay at pH 5.5 or in urine. Resistance was seen with members of the family Enterobacteriaceae, Pseudomonas aeruginosa, and Staphylococcus aureus repeatedly exposed t...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Hirschhorn, L, Neu, H C
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1986
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176452/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3752975/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.30.1.143
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