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Metabolism of ribavirin in respiratory syncytial virus-infected and uninfected cells.

The metabolism of ribavirin to its mono-, di-, and triphosphate derivatives was examined in uninfected and respiratory syncytial virus-infected cells. The degree of phosphorylation was dose dependent upon extracellular ribavirin concentration. The major species formed was the triphosphate, with mono...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Smee, D F, Matthews, T R
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176447/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3752974/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.30.1.117
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