Inositol polyphosphate 4-phosphatase type I regulates cell growth downstream of transcription factor GATA-1

Megakaryocytes lacking transcription factor GATA-1 fail to complete maturation in vivo and hyperproliferate. To define how GATA-1 regulates megakaryocyte cell growth we searched for mRNA transcripts expressed in primary wild-type, but not GATA-1(−), megakaryocytes. One differentially expressed trans...

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Hauptverfasser: Vyas, Paresh, Norris, F. Anderson, Joseph, Raji, Majerus, Philip W., Orkin, Stuart H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2000
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC17638/
https://ncbi.nlm.nih.gov/pubmed/11087841
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