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Increase of interstitial glycerol reflects the degree of ischaemic brain damage: a PET and microdialysis study in a middle cerebral artery occlusion-reperfusion primate model

OBJECTIVE—To evaluate interstitial glycerol as a marker of ischaemia by studying the changes in glycerol in direct relation to changes in regional cerebral metabolic rate of oxygen (CMRO(2)), the lactate/pyruvate ratio (LP ratio), and glutamate.
METHODS—Transorbital 2 hour middle cerebral artery occ...

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Detalhes bibliográficos
Main Authors: Frykholm, P, Hillered, L, Langstrom, B, Persson, L, Valtysson, J, Watanabe, Y, Enblad, P
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1763540/
https://ncbi.nlm.nih.gov/pubmed/11561027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp.71.4.455
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