Relevance of serum protein binding of cefoxitin and cefazolin to their activities against Klebsiella pneumoniae pneumonia in rats.

An experimental Klebsiella pneumoniae pneumonia in rats was used to study the effect of protein binding of cefoxitin and cefazolin on their therapeutic activity. Both cephalosporins were similar with respect to their antimicrobial activity against the K. pneumoniae in vitro, but they differed in the...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Bakker-Woudenberg, I A, van den Berg, J C, Vree, T B, Baars, A M, Michel, M F
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1985
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176351/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3911879/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.28.5.654
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