Pharmacokinetic evaluation of UK-49,858, a metabolically stable triazole antifungal drug, in animals and humans.

The pharmacokinetic profile of UK-49,858 (fluconazole), a novel triazole antifungal agent which is being developed for oral and intravenous use, was determined in mice, rats, dogs, and humans. Comparative data following oral and intravenous administration showed that bioavailability was essentially...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Humphrey, M J, Jevons, S, Tarbit, M H
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1985
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176350/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3004323/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.28.5.648
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