Pharmacokinetics of intravenous amdinocillin in healthy subjects and patients with renal insufficiency.

Five healthy volunteers and 31 patients with various degrees of renal impairment received a 10-mg/kg intravenous dose of amdinocillin by infusion over 15 min to establish the disposition profile of the drug in plasma and urine. Both clearance from plasma and elimination rate constant showed a linear...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Patel, I H, Bornemann, L D, Brocks, V M, Fang, L S, Tolkoff-Rubin, N E, Rubin, R H
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1985
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176307/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4037777/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.28.1.46
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