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Sex related expressivity of the phenotype in coronal craniosynostosis caused by the recurrent P250R FGFR3 mutation

A recurrent point mutation in the fibroblast growth factor receptor 3 (FGFR3) gene that converts proline 250 into arginine is commonly associated with coronal craniosynostosis and has allowed definition of a new syndrome on a molecular basis. Sixty-two patients with sporadic or familial forms of cor...

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Autors principals: Lajeunie, E., El Ghouzzi, V., Le Merrer, M., Munnich, A., Bonaventure, J., Renier, D.
Format: Artigo
Idioma:Inglês
Publicat: BMJ Group 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762958/
https://ncbi.nlm.nih.gov/pubmed/9950359
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