Peroxidase-mediated oxidation of isoniazid.

Oxidation of isonicotinic acid hydrazide (isoniazid) by horseradish peroxidase at the expense of H2O2 yielded reactive species which were able to reduce nitroblue tetrazolium and bleach p-nitrosodimethylaniline. Nicotinic acid hydrazide oxidation did not cause these effects. At slightly alkaline pH,...

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Bibliographic Details

Published in:	Antimicrob Agents Chemother
Main Authors:	Shoeb, H A, Bowman, B U, Ottolenghi, A C, Merola, A J
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 1985
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176284/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3922297/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.27.3.399
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