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Genetic Susceptibility to Type 1 Diabetes in the Intracellular Pathway of Antigen Processing – A Subject Review and Cross-Study Comparison

Ligand binding grooves of MHC class I molecules are able to load a panel of endogenous peptides of varying length and sequence derived from self or foreign origin to activate or deactivate cytotoxic CD8(+) T cells. Peptides are assembled with class I molecules by pathways that are either dependent o...

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Autori principali: Sia, Charles, Weinem, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: SBDR - Society for Biomedical Diabetes Research 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762495/
https://ncbi.nlm.nih.gov/pubmed/17491658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1900/RDS.2005.2.40
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