Persistent Macrophage/Microglial Activation and Myelin Disruption after Experimental Autoimmune Encephalomyelitis in Tissue Inhibitor of Metalloproteinase-1-Deficient Mice

Increased leukocyte trafficking into the parenchyma during inflammatory responses in the central nervous system (CNS) is facilitated by the extracellular proteolytic activities of matrix metalloproteinases that are regulated, in part, by the endogenous tissue inhibitors of metalloproteinases (TIMPs)...

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Detalhes bibliográficos
Main Authors: Crocker, Stephen J., Whitmire, Jason K., Frausto, Ricardo F., Chertboonmuang, Parntip, Soloway, Paul D., Whitton, J. Lindsay, Campbell, Iain L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2006
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762490/
https://ncbi.nlm.nih.gov/pubmed/17148673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.060626
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