Persistent Macrophage/Microglial Activation and Myelin Disruption after Experimental Autoimmune Encephalomyelitis in Tissue Inhibitor of Metalloproteinase-1-Deficient Mice

Increased leukocyte trafficking into the parenchyma during inflammatory responses in the central nervous system (CNS) is facilitated by the extracellular proteolytic activities of matrix metalloproteinases that are regulated, in part, by the endogenous tissue inhibitors of metalloproteinases (TIMPs)...

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Bibliographische Detailangaben
Hauptverfasser: Crocker, Stephen J., Whitmire, Jason K., Frausto, Ricardo F., Chertboonmuang, Parntip, Soloway, Paul D., Whitton, J. Lindsay, Campbell, Iain L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2006
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Regular Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762490/
https://ncbi.nlm.nih.gov/pubmed/17148673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.060626
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