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Overexpression of Heme Oxygenase-1 in Murine Melanoma : Increased Proliferation and Viability of Tumor Cells, Decreased Survival of Mice
Heme oxygenase-1 (HO-1), a cytoprotective enzyme, can be induced in tumors in response to anti-cancer therapies. We investigated the role of HO-1 in B16(F10), S91, and Sk-mel188 melanoma cells. Overexpression of HO-1 after transduction with adenoviral vectors increased cell proliferation, resistance...
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Главные авторы: | , , , , , , , , , , , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
American Society for Investigative Pathology
2006
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1762485/ https://ncbi.nlm.nih.gov/pubmed/17148680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.051365 |
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