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Eosinophils and CCR3 Regulate Interleukin-13 Transgene-Induced Pulmonary Remodeling

Interleukin (IL)-13 transgene overexpression in the lung induces features of chronic inflammatory lung disorders, including an eosinophil-rich inflammatory cell infiltration, airway hyper-reactivity, and remodeling of the airway (eg, subepithelial fibrosis, goblet cell metaplasia, and smooth muscle...

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Bibliographic Details
Main Authors: Fulkerson, Patricia C., Fischetti, Christine A., Rothenberg, Marc E.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762480/
https://ncbi.nlm.nih.gov/pubmed/17148674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.060617
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