IL-7 Up-Regulates TNF-α-Dependent Osteoclastogenesis in Patients Affected by Solid Tumor

BACKGROUND: Interleukin-7 (IL-7) is a potent regulator of lymphocyte development, which has also significant effects on bone; in fact it is a potent osteoclastogenic factor. Some human solid tumors produce high IL-7 levels, suggesting a potential IL-7 role on tumor development and progression. METHO...

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Bibliografische gegevens
Hoofdauteurs: Roato, Ilaria, Brunetti, Giacomina, Gorassini, Eva, Grano, Maria, Colucci, Silvia, Bonello, Lisa, Buffoni, Lucio, Manfredi, Roberto, Ruffini, Enrico, Ottaviani, Davide, Ciuffreda, Libero, Mussa, Antonio, Ferracini, Riccardo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2006
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762428/
https://ncbi.nlm.nih.gov/pubmed/17205128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000124
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