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Requirement of TORC1 for Late-Phase Long-Term Potentiation in the Hippocampus

Late-phase long-term potentiation (L-LTP) and long-term memory depend on the transcription of mRNA of CRE-driven genes and synthesis of proteins. However, how synaptic signals propagate to the nucleus is unclear. Here we report that the CREB coactivator TORC1 (transducer of regulated CREB activity 1...

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Detalhes bibliográficos
Main Authors: Zhou, Yang, Wu, Hao, Li, Shuai, Chen, Qian, Cheng, Xue-Wen, Zheng, Jing, Takemori, Hiroshi, Xiong, Zhi-Qi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762377/
https://ncbi.nlm.nih.gov/pubmed/17183642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000016
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