Antimyocarditic activity of the guanine derivative BIOLF-70 in a coxsackievirus B3 murine model.

Prophylactic administration of a nontoxic dose of 9-[[2-benzyloxyl-1-(benzyloxymethyl)ethoxy]methyl]-6-chlo roguanine (BIOLF-70) to mice reduced the number of myocarditic lesions induced by coxsackievirus B3 (CVB3). BIOLF-70 exhibited minimal antiviral activity against CVB3 in HeLa cells and murine...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Gauntt, C J, Arizpe, H M, Kung, J T, Ogilvie, K K, Cheriyan, U O
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1985
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176235/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2580480/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.27.2.184
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