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Efficient Non-Viral Ocular Gene Transfer with Compacted DNA Nanoparticles

BACKGROUND: The eye is an excellent candidate for gene therapy as it is immune privileged and much of the disease-causing genetics are well understood. Towards this goal, we evaluated the efficiency of compacted DNA nanoparticles as a system for non-viral gene transfer to ocular tissues. The compact...

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Detalhes bibliográficos
Main Authors: Farjo, Rafal, Skaggs, Jeff, Quiambao, Alexander B., Cooper, Mark J., Naash, Muna I.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762345/
https://ncbi.nlm.nih.gov/pubmed/17183666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000038
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