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Identification of the monomeric G-protein, Rhes, as an efaroxan-regulated protein in the pancreatic β-cell

1. Efaroxan induces membrane depolarization by interaction with the pore forming subunit of the ATP-sensitive potassium channel, Kir6.2. However, this effect is not responsible for its full secretory activity. 2. In this study we have used an anti-idiotypic approach to generate antibodies that recog...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chan, Sue L F, Monks, Lara K, Gao, Hongwei, Deaville, Pamela, Morgan, Noel G
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762110/
https://ncbi.nlm.nih.gov/pubmed/11976265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704680
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