Contrasting effects of VEGF gene disruption in embryonic stem cell-derived versus oncogene-induced tumors

Previous gene targeting studies have implicated an indispensable role of vascular endothelial growth factor (VEGF) in tumor angiogenesis, particularly in tumors of embryonal or endocrine origin. In contrast, we report here that transformation of VEGF-deficient adult fibroblasts (MDF528) with ras or...

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Huvudupphovsmän: Viloria-Petit, Alicia, Miquerol, Lucile, Yu, Joanne L., Gertsenstein, Marina, Sheehan, Capucine, May, Linda, Henkin, Jack, Lobe, Corrinne, Nagy, Andras, Kerbel, Robert S., Rak, Janusz
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2003
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC176189/
https://ncbi.nlm.nih.gov/pubmed/12912908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg408
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