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Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG

The human 3-methyladenine DNA glycosylase [alkyladenine DNA glycosylase (AAG)] catalyzes the first step of base excision repair by cleaving damaged bases from DNA. Unlike other DNA glycosylases that are specific for a particular type of damaged base, AAG excises a chemically diverse selection of sub...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Lau, Albert Y., Wyatt, Michael D., Glassner, Brian J., Samson, Leona D., Ellenberger, Tom
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2000
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17617/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11106395/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.25.13573
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