Zinc plays a key role in human and bacterial GTP cyclohydrolase I

The crystal structure of recombinant human GTP cyclohydrolase I was solved by Patterson search methods by using the coordinates of the Escherichia coli enzyme as a model. The human as well as bacterial enzyme were shown to contain an essential zinc ion coordinated to a His side chain and two thiol g...

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Detalhes bibliográficos
Main Authors: Auerbach, Günter, Herrmann, Anja, Bracher, Andreas, Bader, Gerd, Gütlich, Markus, Fischer, Markus, Neukamm, Martin, Garrido-Franco, Marta, Richardson, John, Nar, Herbert, Huber, Robert, Bacher, Adelbert
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC17616/
https://ncbi.nlm.nih.gov/pubmed/11087827
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