Secretion of Shigella flexneri Ipa invasins on contact with epithelial cells and subsequent entry of the bacterium into cells are growth stage dependent.
Upon contact with the surface of epithelial cells, Shigella flexneri secretes Ipa proteins through the Mxi-Spa type III secretion apparatus. Among the Ipa proteins, IpaB and IpaC form a soluble complex in the bacterial supernatant which appears to be sufficient to initiate the cellular rearrangement...
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| Опубликовано в:: | Infect Immun |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology (ASM)
1997
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176124/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9009341/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.2.774-782.1997 |
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