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Simultaneous prevention of glutamine synthesis and high-affinity transport attenuates Salmonella typhimurium virulence.

In Salmonella typhimurium, transcription of the glnA gene (encoding glutamine synthetase) is under the control of the nitrogen-regulatory (ntr) system comprising the alternate sigma factor sigma54 (NtrA) and the two-component sensor-transcriptional activator pair NtrB and NtrC. The glnA, ntrB, and n...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Principais autores: Klose, K E, Mekalanos, J J
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1997
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176100/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9009317/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.2.587-596.1997
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