Simultaneous prevention of glutamine synthesis and high-affinity transport attenuates Salmonella typhimurium virulence.
In Salmonella typhimurium, transcription of the glnA gene (encoding glutamine synthetase) is under the control of the nitrogen-regulatory (ntr) system comprising the alternate sigma factor sigma54 (NtrA) and the two-component sensor-transcriptional activator pair NtrB and NtrC. The glnA, ntrB, and n...
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| Udgivet i: | Infect Immun |
|---|---|
| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1997
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176100/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9009317/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.2.587-596.1997 |
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