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Nitric oxide-releasing flurbiprofen reduces formation of proinflammatory hydrogen sulfide in lipopolysaccharide-treated rat

1. The biosynthesis of both nitric oxide (NO) and hydrogen sulfide (H(2)S) is increased in lipopolysaccharide (LPS)-injected mice and rats but their interaction in these models is not known. In this study we examined the effect of the NO donor, nitroflurbiprofen (and the parent molecule flurbiprofen...

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Main Authors: Anuar, Farhana, Whiteman, Matthew, Siau, Jia Ling, Kwong, Shing Erl, Bhatia, Madhav, Moore, Philip K
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1760720/
https://ncbi.nlm.nih.gov/pubmed/16491094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706696
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