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Comparison of single-dose treatment with norfloxacin and standard 5-day treatment with trimethoprim-sulfamethoxazole for acute shigellosis in adults.

Shigellae have been shown to be highly susceptible to new quinolone agents, with average MICs for 90% of isolates of less than 0.1 microgram/ml. Because these agents also reach high concentrations in the stool after a single dose, the effectiveness of a single 800-mg dose of norfloxacin and of 5-day...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Gotuzzo, E, Oberhelman, R A, Maguiña, C, Berry, S J, Yi, A, Guzman, M, Ruiz, R, Leon-Barua, R, Sack, R B
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176069/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2675757/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.7.1101
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