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Endothelin generating pathway through endothelin(1–31) in human cultured bronchial smooth muscle cells

1. The effects of endothelin (ET)-1(1–31) and ET-2(1–31), human chymase products of the corresponding big ETs, on the intracellular free Ca(2+) concentration ([Ca(2+)](i)) and [(125)I]-ET-1 binding were investigated using human cultured bronchial smooth muscle cells (BSMC). 2. ET-1(1–31) (10(−8) M –...

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Huvudupphovsmän: Hayasaki-Kajiwara, Yoko, Naya, Noriyuki, Shimamura, Toshitake, Iwasaki, Takanori, Nakajima, Masatoshi
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1999
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1760661/
https://ncbi.nlm.nih.gov/pubmed/10455291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702664
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