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Presynaptic inhibition preferentially reduces the NMDA receptor-mediated component of transmission in rat midbrain dopamine neurons

1. We used patch pipettes to record whole-cell currents from single dopamine neurons in slices of rat midbrain. Pharmacological methods were used to isolate EPSCs evoked by focal electrical stimulation. 2. Baclofen was significantly more potent for inhibiting NMDA receptor-mediated EPSCs (IC(50)=0.2...

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Detaylı Bibliyografya
Asıl Yazarlar: Wu, Yan-Na, Shen, Ke-Zhong, Johnson, Steven W
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1999
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1760653/
https://ncbi.nlm.nih.gov/pubmed/10455292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702680
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