Mechanism of action of cephalosporins and resistance caused by decreased affinity for penicillin-binding proteins in Bacteroides fragilis.

The susceptibilities of 52 clinical isolates of Bacteroides fragilis to five monoanionic cephalosporins were examined. Cefoperazone showed the highest antibacterial activity, followed by ceftezole, cefazolin, cefamandole, and cephalothin. There were two groups of resistant strains: one group (ca. 15...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Yotsuji, A, Mitsuyama, J, Hori, R, Yasuda, T, Saikawa, I, Inoue, M, Mitsuhashi, S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176031/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3266730/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.32.12.1848
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