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The cryptic tetracycline resistance determinant on Tn4400 mediates tetracycline degradation as well as tetracycline efflux.

Escherichia coli containing the cryptic tetracycline resistance determinant (class F) from the Bacteroides fragilis transposon Tn4400 on plasmid pGAT400 expressed a detoxification of tetracycline as well as an active efflux of tetracycline. This finding concurs with the report of detoxification for...

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Pubblicato in:Antimicrob Agents Chemother
Autori principali: Park, B H, Levy, S B
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1988
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176021/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3072922/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.32.12.1797
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