Selective inhibition of COX-2 in humans is associated with less gastrointestinal injury: a comparison of nimesulide and naproxen

BACKGROUND—Selective inhibitors of cyclooxygenase (COX)-2 may provoke less gastric damage and platelet inhibition than conventional non-steroidal anti-inflammatory drugs.
AIMS—We compared the biochemical and gastrointestinal effects of nimesulide, a potent and selective COX-2 inhibitor, with naproxe...

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Detalhes bibliográficos
Main Authors: Shah, A, Thjodleifsson, B, Murray, F, Kay, E, Barry, M, Sigthorsson, G, Gudjonsson, H, Oddsson, E, Price, A, Fitzgerald, D, Bjarnason, I
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1760142/
https://ncbi.nlm.nih.gov/pubmed/11171823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.48.3.339
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