In vitro and in vivo evidence that the antiviral activity of 2',3'-dideoxycytidine is target cell dependent in a feline retrovirus animal model.

2',3'-Dideoxycytidine (DDC) was evaluated for prophylactic antiviral activity in vitro and in vivo, using the feline leukemia virus (FeLV)-cat animal model. In vitro antiviral activity of DDC against FeLV was dependent upon the target cell used for infection. DDC (5 to 10 microM) inhibited FeLV infe...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Polas, P J, Swenson, C L, Sams, R, Cheney, C M, Hayes, K A, Tarr, M J, Kociba, G J, Mathes, L E
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175992/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2167039/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.7.1414
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