Structure-activity relationships of analogs of pentamidine against Plasmodium falciparum and Leishmania mexicana amazonensis.

The antiprotozoal compound 1,5-di(4-amidinophenoxy)pentane (pentamidine) and 36 of its analogs were screened for in vitro activity against Leishmania mexicana amazonensis clone 669 C4S (MHOM/BR/73/M2269) and Plasmodium falciparum clones W2 (Indochina III/CDC) and D6 (Sierra Leone I/CDC). Pentamidine...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Bell, C A, Hall, J E, Kyle, D E, Grogl, M, Ohemeng, K A, Allen, M A, Tidwell, R R
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1990
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175985/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2201254/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.7.1381
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